But Professor Stephen Hawking was filmed auditioning a host of A-listers for a new voice as part of a humorous Red Nose Day sketch.
Rebel Wilson, Liam Neeson and Eddie Redmayne were among those who took part in the skit.
Explaining his search for a new voice, Professor Hawking - who has used the same trademarked voice for over 30 years - said: 'I felt it was time for a voice upgrade so I asked Comic Relief to help me out.'
But he apparently wasn't impressed by the auditions, adding: 'I probably shouldn’t have bothered, as these celebrities are a right bunch of jokers.
After unveiling his choice of his new voice, he said: 'I’m pretty happy with my new voice though, I think it’ll give my lectures a bit more oomph.’
In the clip, various celebrities are seen explaining to the physicist why they should be picked.
Taken star Liam - who is also starring in the Love Actually special for Red Nose Day - says: 'Stephen, it's me. Surely it has to be me. Listen to my voice - it's deep, it's sexy, it's got a tinge of physics.'
Meanwhile, Rebel starts her audition by saying: 'Hi, I'm Rebel Wilson and I'm reading for the role of Stephen Hawking. He's a really smart guy, so I think we'd be the perfect match really.'
And Eddie - who famously played the scientist in The Theory of Everything - is annoyed that he even has to audition.
He says: 'So what is it, like a sequel? If they want me to go through that again, they're going to have to pay me a shedload of cash.'
Other celebrities to audition include Kylie Minogue, Anna Kendrick, Stephen Fry, Simon Cowell, Gordon Ramsay, Felicity Jones, Geri Halliwell, Andrew Lloyd Webber - and even Miss Piggy.
This year's Red Nose Day, which takes place on Friday night, is hotly anticipated due to the 10-minute sequel of Love Actually, written by Richard Curtis.
The stars of the film - including the likes of Keira Knightley, Martine McCutcheon, Andrew Lincoln, Hugh Grant and Liam Neeson - have reprised their roles after 14 years.
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